As soon as the temperature drops my fingertips crack! It is very painful. My hands dry out too. Here are a few things that may help if you have the same problem: pick a hand sanitizer made with jojoba oil. This is rich in vitamin E so it counteracts the drying alcohol and the wax esters mimic the skin’s natural oils to keep your hands hydrated. The best hand soap to use is one that contains a probiotic to keep skin healthy. And lastly, the best hand cream to use is one that contains vitamin B-3 to prevent future water loss.